List of Selected Publications (2011- present)
2020
Tang W, Bronner ME. Neural crest lineage analysis: from past to future trajectory. Development. 2020. PMID: 33097550
Li Y, Gonzalez WG, Andreev A, Tang W, Gandhi S, Cunha A, Prober D, Lois C, Bronner ME. Macropinocytosis-mediated membrane recycling drives neural crest migration by delivering F-actin to the lamellipodium. Proc Natl Acad Sci U S A. 2020. PMID: 33087579
Gandhi S, Hutchins EJ, Maruszko K, Park JH, Thomson M, Bronner ME. Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration. Elife. 2020 Sep 23;9:e57779.
Niklasson CU, Fredlund E, Monni E, Lindvall JM, Kokaia Z, Hammarlund EU, Bronner ME, Mohlin S. Hypoxia inducible factor-2α importance for migration, proliferation, and self-renewal of trunk neural crest cells. Dev Dyn. 2020 Sep 17.
Hutchins EJ, Bronner ME. A Spectrum of Cell States During the Epithelial-to-Mesenchymal Transition. Methods Mol Biol. 2021;2179:3-6.
Stundl J, Pospisilova A, Matějková T, Psenicka M, Bronner ME, Cerny R. Migratory patterns and evolutionary plasticity of cranial neural crest cells in ray-finned fishes. Dev Biol. 2020 Nov 1;467(1-2):14-29.
El-Nachef WN, Bronner ME. De novo enteric neurogenesis in post-embryonic zebrafish from Schwann cell precursors rather than resident cell types. Development. 2020 Jul 13;147(13):dev186619. doi: 10.1242/dev.186619.
Piacentino ML, Li Y, Bronner ME. Epithelial-to-mesenchymal transition and different migration strategies as viewed from the neural crest. Curr Opin Cell Biol. 2020 Oct;66:43-50. doi: 10.1016/j.ceb.2020.05.001. Epub 2020 Jun 9.
Gandhi S, Ezin M, Bronner ME. Reprogramming Axial Level Identity to Rescue Neural-Crest-Related Congenital Heart Defects. Dev Cell. 2020 May 4;53(3):300-315.e4. doi: 10.1016/j.devcel.2020.04.005.
Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, García de Herreros A, Goodall GJ, Hadjantonakis AK, Huang RJY, Kalcheim C, Kalluri R, Kang Y, Khew-Goodall Y, Levine H, Liu J, Longmore GD, Mani SA, Massagué J, Mayor R, McClay D, Mostov KE, Newgreen DF, Nieto MA, Puisieux A, Runyan R, Savagner P, Stanger B, Stemmler MP, Takahashi Y, Takeichi M, Theveneau E, Thiery JP, Thompson EW, Weinberg RA, Williams ED, Xing J, Zhou BP, Sheng G; EMT International Association (TEMTIA). Guidelines and definitions for research on epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2020 Jun;21(6):341-352. doi: 10.1038/s41580-020-0237-9. Epub 2020 Apr 16.
Mehrotra P, Tseropoulos G, Bronner ME, Andreadis ST. Adult tissue-derived neural crest-like stem cells: Sources, regulatory networks, and translational potential. Stem Cells Transl Med. 2020 Mar;9(3):328-341. doi: 10.1002/sctm.19-0173. Epub 2019 Nov 18.
2019
Martik ML, Gandhi S, Uy BR, Gillis JA, Green SA, Simoes-Costa M, Bronner ME. Evolution of the new head by gradual acquisition of neural crest regulatory circuits. Nature. 2019 Oct;574(7780):675-678. doi: 10.1038/s41586-019-1691-4. Epub 2019 Oct 23.
Hockman D, Chong-Morrison V, Green SA, Gavriouchkina D, Candido-Ferreira I, Ling ITC, Williams RM, Amemiya CT, Smith JJ, Bronner ME, Sauka-Spengler T. A genome-wide assessment of the ancestral neural crest gene regulatory network. Nat Commun. 2019 Oct 16;10(1):4689. doi: 10.1038/s41467-019-12687-4.
Prummel KD, Hess C, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Czarkwiani A, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C. A conserved regulatory program initiates lateral plate mesoderm emergence across chordates. Nat Commun. 2019 Aug 26;10(1):3857. doi: 10.1038/s41467-019-11561-7.
Tang W, Martik ML, Li Y, Bronner ME. Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish. Elife. 2019 Aug 8;8:e47929. doi: 10.7554/eLife.47929.
Moghadasi Boroujeni S, Koontz A, Tseropoulos G, Kerosuo L, Mehrotra P, Bajpai VK, Selvam SR, Lei P, Bronner ME, Andreadis ST. Neural crest stem cells from human epidermis of aged donors maintain their multipotency in vitro and in vivo. Sci Rep. 2019 Jul 5;9(1):9750. doi: 10.1038/s41598-019-46140-9.
Soldatov R, Kaucka M, Kastriti ME, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Häring M, Dyachuk V, Bock C, Farlik M, Piacentino ML, Boismoreau F, Hilscher MM, Yokota C, Qian X, Nilsson M, Bronner ME, Croci L, Hsiao WY, Guertin DA, Brunet JF, Consalez GG, Ernfors P, Fried K, Kharchenko PV, Adameyko I. Spatiotemporal structure of cell fate decisions in murine neural crest. Science. 2019 Jun 7;364(6444):eaas9536. doi: 10.1126/science.aas9536.
Parker HJ, Bronner ME, Krumlauf R. An atlas of anterior hox gene expression in the embryonic sea lamprey head: Hox-code evolution in vertebrates. Dev Biol. 2019 Sep 1;453(1):19-33. doi: 10.1016/j.ydbio.2019.05.001. Epub 2019 May 6.
Diaz RE Jr, Shylo NA, Roellig D, Bronner M, Trainor PA. Filling in the phylogenetic gaps: Induction, migration, and differentiation of neural crest cells in a squamate reptile, the veiled chameleon (Chamaeleo calyptratus). Dev Dyn. 2019 Aug;248(8):709-727. doi: 10.1002/dvdy.38. Epub 2019 Apr 29.
Sánchez-Vásquez E, Bronner ME, Strobl-Mazzulla PH. Epigenetic inactivation of miR-203 as a key step in neural crest epithelial-to-mesenchymal transition. Development. 2019 Apr 11;146(7):dev171017. doi: 10.1242/dev.171017.
Tang W, Li Y, Gandhi S, Bronner ME. Multiplex clonal analysis in the chick embryo using retrovirally-mediated combinatorial labeling. Dev Biol. 2019 Jun 1;450(1):1-8. doi: 10.1016/j.ydbio.2019.03.007. Epub 2019 Mar 15.
Parker HJ, De Kumar B, Green SA, Prummel KD, Hess C, Kaufman CK, Mosimann C, Wiedemann LM, Bronner ME, Krumlauf R. A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates. Nat Commun. 2019 Mar 13;10(1):1189. doi: 10.1038/s41467-019-09197-8.
Hutchins EJ, Bronner ME. Draxin alters laminin organization during basement membrane remodeling to control cranial neural crest EMT. Dev Biol. 2019 Feb 15;446(2):151-158. doi: 10.1016/j.ydbio.2018.12.021. Epub 2018 Dec 21.
2018
Gandhi S and Bronner ME. Insights into neural crest development from studies of avian embryos. 2018 Int J Dev Biol. 62(1-2-3):183-194. doi: 10.1387/ijdb.180038sg.
2017
Lignell A*, Kerosuo L*, Streichan SJ, Cai L, Bronner ME. Identification of a neural crest stem cell niche by Spatial Genomic Analysis. Nat Commun. 2017 28;8(1):1830. doi: 10.1038/s41467-017-01561-w.
Li, Y., Li. A., Junge, J., and Bronner, M.E. Planar cell polarity signaling coordinates oriented cell division and cell rearrangement in clonally expanding growth plate cartilage. 2017. eLife e23279.
Gandhi S, Piacentino ML, Vieceli FM, Bronner ME. Optimization of CRISPR/Cas9 genome editing for loss-of-function in the early chick embryo. 2017 Dev Biol. 432(1):86-97. doi: 10.1016/j.ydbio.2017.08.036.
Uribe, R., Hong, S.S., and Bronner M.E. Retinoic acid temporally orchestrates colonization of the gut by vagal neural crest cells. 2017. Dev. Biol. 433(1):17-32
Suarez-Bregua, P., Saxena, A., Bronner, M.E., Moran, P. and Rotllant, J. 2017. Targeted Pth4-expressing cell ablation impairs skeletal mineralization in zebrafish. PLoS One: e0186444.
Martik, M. and Bronner, ME. Regulatory Logic Underlying Diversification of the Neural Crest. 2017. Trends in Genetics (17)30132-4.
Green SA, Uy BR and Bronner ME. Ancient evolutionary origin of vertebrate enteric neurons from trunk-derived neural crest. Nature 2017 Mar 20. doi: 10.1038/nature21679
Roellig D, Tan-Cabugao J, Esaian S, Bronner ME. Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells. Elife. 2017 Mar 29;6. pii: e21620. doi: 10.7554/eLife.21620.
Chen J, Tambalo M, Barembaum M, Ranganathan R, Simões-Costa M, Bronner ME, Streit A. A systems level approach reveals new gene regulatory modules in the developing ear. 2017. Development 44(8):1531-1543
Bajpai VK, Kerosuo L, Tseropoulos G, Cummings KA, Wang X, Lei P, Liu B, Liu S, Popescu G, Bronner ME, Andreadis ST. Reprogramming Postnatal Human Epidermal Keratinocytes toward Functional Neural Crest Fates. 2017. Stem Cells35(5):1402-1415
Murko C and Bronner ME. Tissue specific regulation of the chick Sox10E1 enhancer by different Sox family members. 2017. Dev Biol. Feb 1;422(1):47-57. doi: 10.1016/j.ydbio.2016.12.004
Suarez-Bregua, P, Torres-Nunez, E, Saxena, A., Gueerreiro, P, Braasch, I, Prober, D., Moran, P., Cerda-Reverter, J., Du., S, Adrio, F., Power, D, Cannario, A., Postlethweit, J, Bronner, M., Canestro C. and Rotllant, J. Pth4, an ancient Parathyroid Hormone lost in eutherian mammals, reveals a new brain-to-bone signaling pathway. 2017. FASEB Journal 31(2):569-583.
2016
Kerosuo L and Bronner ME. cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool. 2016. Cell Reports. Dec 6;17(10):2648-2659. doi: 10.1016/j.celrep.2016.11.025
Simoes-Costa M and Bronner ME. Reprogramming of avian neural crest axial identity and cell fate. Science. 2016 Jun 24;352(6293):1570-3. doi: 10.1126/science.aaf2729.
Uribe RA, Gu T and Bronner ME. A novel subset of enteric neurons revealed by ptf1a:GFP in the developing zebrafish enteric nervous system. Genesis 2016 Feb 10. doi: 10.1002/dvg.22927
Roellig D and Bronner ME. The epigenetic modifier DNMT3A is necessary for proper otic placode formation. Developmental Biology 2016 Jan 28. pii: S0012-1606(16)30038-0. doi: 10.1016/j.ydbio.2016.01.034.
2015
Uribe RA*, Buzzi AL*, Strobl-Mazzulla and Bronner ME. Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression. Journal of Cell Biology. 2015 Nov 23;211(4):815-27. doi: 10.1083/jcb.201503071
Kerosuo L, Nie S, Bajpai R, Bronner ME. Crestospheres: Long-Term Maintenance of Multipotent, Premigratory Neural Crest Stem Cells. Stem Cell Reports. 2015 Sep 29 pii: S2213-6711(15)00251-9. doi: 10.1016/j.stemcr.2015.08.017.
Uribe RA and Bronner ME. Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development. Molecular Biology of the Cell. 2015 Sep 9. doi:10.1091/mbc.E15-02-0112.
Simoes-Costa M, Stone M and Bronner ME. Axud1 Integrates Wnt Signaling and Transcriptional Inputs to Drive Neural Crest Formation. Developmental Cell. 2015 Aug 5. pii: S1534-5807(15)00451-7. doi: 10.1016/j.devcel.2015.06.024.
Green, SA, Simoes-Costa M, and Bronner ME. Evolution of vertebrates as viewed from the crest. Nature. 2015 Apr 23, 2015.
Nie, S and Bronner ME. Dual developmental role of transcriptional regulator Ets1 in Xenopus cardiac vs. heart mesoderm. Cardiovas Res. 2015 Feb 17.
Hochgreb-Hägele T, Koo DE, Bronner ME. Znf385C mediates a novel p53-dependent transcriptional switch to control timing of facial bone formation. Dev Biol. 2015 Apr 1.
Simoes-Costa M and Bronner ME. Establishing a neural crest identify: a gene regulatory recipe. Development. 2015 Jan 15.
Uy BR, Simoes-Costa M, Koo DE, Sauka-Spengler T, Bronner ME. Evolutionarily conserved role for SoxC genes in neural crest specification and neuronal differentiation. Dev Biol. 2015 Jan 15.
2014
Hu N, Strobl-Mazzulla PH, Simoes-Costa M, Sánchez-Vásquez E, Bronner ME. DNA methyltransferase 3B regulates duration of neural crest production via repression of Sox10. PNAS. 2014 Dec 16.
Ezin M, Barembaum M, Bronner ME. Stage-dependent plasticity of the anterior neural folds to form neural crest. Differentiation. 2014 Sep-Oct.
Saxena A, Bronner ME. A novel HoxB cluster protein expressed in the hindbrain and pharyngeal arches. Genesis. 2014 Oct.
Wang K, Milkie DE, Saxena A, Engerer P, Misgeld T, Bronner ME, Mumm J, Betzig E. Rapid adaptive optical recovery of optimal resolution over large volumes. Nature Methods. 2014 Jun;11(6):625-8. doi: 10.1038/nmeth.2925.
Green SA and Bronner ME. The lamprey: a jawless vertebrate model system for examining origin of the neural crest and other vertebrate traits. Differentiation. 2014 Jan-Feb;87(1-2):44-51. doi: 10.1016/j.diff.2014.02.001
Hochgreb-Hägele T, Koo DE, Das NM, Bronner ME. Zebrafish stem/progenitor factor msi2b exhibits two phases of activity mediated by different splice variants. Stem Cells. 2014 Feb;32(2):558-71. doi: 10.1002/stem.1583
Simões-Costa M, Tan-Cabugao J, Antoshechkin I, Sauka-Spengler T, Bronner ME. Transcriptome analysis reveals novel players in the cranial neural crest gene regulatory network. Genome Res. 2014 Feb;24(2):281-90. doi: 10.1101/gr.161182.113
2013
Kerosuo L and Bronner ME. Biphasic influence of Miz1 on neural crest development by regulating cell survival and apical adhesion complex formation in the developing neural tube. Mol Biol Cell. 2013 Dec 4.
Rogers CD, Saxena A, Bronner ME. Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT. J Cell Biol. 2013 Dec 9;203(5):835-47. doi: 10.1083/jcb.201305050. Epub 2013 Dec 2.
Barembaum M, Bronner ME. Identification and dissection of a key enhancer mediating cranial neural crest specific expression of transcription factor, Ets-1. Dev Biol. 2013 Oct 15.
Saxena A, Peng BN, Bronner ME. Sox10-dependent neural crest origin of olfactory microvillous neurons in zebrafish. eLife, 2:e00336 (2013). dx.doi.org/10.7554/eLife.00336
Simões-Costa MS, McKeown SJ, Tan-Cabugao J, Sauka-Spengler T, Bronner ME. Dynamic and Differential Regulation of Stem Cell Factor FoxD3 in the Neural Crest Is Encrypted in the Genome. PLoS Genet. 2012 Dec;8(12):e1003142. doi: 10.1371/journal.pgen.1003142. Epub 2012 Dec 20.
Rogers CD, Phillips JL, Bronner ME (2012). Elk3 is essential for the progression from progenitor to definitive neural crest cell. Dev Biol. 2012 Dec 22. pii: S0012-1606(12)00675-6. doi: 10.1016/j.ydbio.2012.12.009. Feb 15, 2012.
Hochgreb-Hägele T, Bronner ME (2012). A novel FoxD3 gene trap line reveals neural crest precursor movement and a role for FoxD3 in their specification. Dev Biol. 2013 Feb 1;374(1):1-11. doi: 10.1016/j.ydbio.2012.11.035. Feb 1, 2012.
2012
Hu N, Strobl-Mazzulla P, Sauka-Spengler T, Bronner ME (2012). DNA methyltransferase3A as a molecular switch mediating the neural tube-to-neural crest fate transition. Genes Dev. 2012 Nov 1;26(21):2380-5. doi: 10.1101/gad.198747.112.
Jayasena CS, Bronner ME (2012). Rbms3 functions in craniofacial development by posttranscriptionally modulating TGF-β signaling. J Cell Biol. 2012 Oct 29;199(3):453-66. doi: 10.1083/jcb.201204138. Epub 2012 Oct 22.
Strobl-Mazzulla PH, Bronner ME (2012). A PHD12-Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition. J Cell Biol. 2012 Sep 17;198(6):999-1010. doi: 10.1083/jcb.201203098.
2011
Trinh le A, Hochgreb T, Graham M, Wu D, Ruf-Zamojski F, Jayasena CS, Saxena A, Hawk R, Gonzalez-Serricchio A, Dixson A, Chow E, Gonzales C, Leung HY, Solomon I, Bronner-Fraser M, Megason SG, Fraser SE. (2011) A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Genes Dev. Nov 1;25(21):2306-20. PMID: 22056673.
Betancur P, Sauka-Spengler T, Bronner M (2011) A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs. Development. 2011 Jul 20 PMID: 21775416
Haming D., Simoes-Costa M., Uy B., Sauka-Spengler T., Bronner ME. (2011) Expression of sympathetic nervous system genes in lamprey suggests their recruitment for specification of a new vertebrate feature. PLoS One. 2011;6(10):e26543. PMID:22046306
Jayasena CS, Trinh LA, Bronner M. (2011) Live imaging of endogenous Collapsin response mediator protein-1 expression at subcellular resolution during zebrafish nervous system development. Gene Expr Patterns. May 24 PMID: 21628002
McCabe, K.L. and Bronner-Fraser, M. (2011) Molecular and tissue interactions governing induction of cranial ectodermal placodes. Dev. Biol. 332:189-95 PMID: 19500565
Nie S., Kee Y., Bronner-Fraser M. (2011) Caldesmon regulates actin dynamics to influence cranial neural crest migration in Xenopus. Mol Biol Cell. 22, 3355-65. PMID: 21795398
Nikitina N., Tong L., Bronner ME. (2011) Ancestral network module regulating prdm1 expression in the lamprey neural plate border. Dev Dyn. 240, 2265-71. PMID: 21932309
Tang W, Bronner ME. Neural crest lineage analysis: from past to future trajectory. Development. 2020. PMID: 33097550
Li Y, Gonzalez WG, Andreev A, Tang W, Gandhi S, Cunha A, Prober D, Lois C, Bronner ME. Macropinocytosis-mediated membrane recycling drives neural crest migration by delivering F-actin to the lamellipodium. Proc Natl Acad Sci U S A. 2020. PMID: 33087579
Gandhi S, Hutchins EJ, Maruszko K, Park JH, Thomson M, Bronner ME. Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration. Elife. 2020 Sep 23;9:e57779.
Niklasson CU, Fredlund E, Monni E, Lindvall JM, Kokaia Z, Hammarlund EU, Bronner ME, Mohlin S. Hypoxia inducible factor-2α importance for migration, proliferation, and self-renewal of trunk neural crest cells. Dev Dyn. 2020 Sep 17.
Hutchins EJ, Bronner ME. A Spectrum of Cell States During the Epithelial-to-Mesenchymal Transition. Methods Mol Biol. 2021;2179:3-6.
Stundl J, Pospisilova A, Matějková T, Psenicka M, Bronner ME, Cerny R. Migratory patterns and evolutionary plasticity of cranial neural crest cells in ray-finned fishes. Dev Biol. 2020 Nov 1;467(1-2):14-29.
El-Nachef WN, Bronner ME. De novo enteric neurogenesis in post-embryonic zebrafish from Schwann cell precursors rather than resident cell types. Development. 2020 Jul 13;147(13):dev186619. doi: 10.1242/dev.186619.
Piacentino ML, Li Y, Bronner ME. Epithelial-to-mesenchymal transition and different migration strategies as viewed from the neural crest. Curr Opin Cell Biol. 2020 Oct;66:43-50. doi: 10.1016/j.ceb.2020.05.001. Epub 2020 Jun 9.
Gandhi S, Ezin M, Bronner ME. Reprogramming Axial Level Identity to Rescue Neural-Crest-Related Congenital Heart Defects. Dev Cell. 2020 May 4;53(3):300-315.e4. doi: 10.1016/j.devcel.2020.04.005.
Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, García de Herreros A, Goodall GJ, Hadjantonakis AK, Huang RJY, Kalcheim C, Kalluri R, Kang Y, Khew-Goodall Y, Levine H, Liu J, Longmore GD, Mani SA, Massagué J, Mayor R, McClay D, Mostov KE, Newgreen DF, Nieto MA, Puisieux A, Runyan R, Savagner P, Stanger B, Stemmler MP, Takahashi Y, Takeichi M, Theveneau E, Thiery JP, Thompson EW, Weinberg RA, Williams ED, Xing J, Zhou BP, Sheng G; EMT International Association (TEMTIA). Guidelines and definitions for research on epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2020 Jun;21(6):341-352. doi: 10.1038/s41580-020-0237-9. Epub 2020 Apr 16.
Mehrotra P, Tseropoulos G, Bronner ME, Andreadis ST. Adult tissue-derived neural crest-like stem cells: Sources, regulatory networks, and translational potential. Stem Cells Transl Med. 2020 Mar;9(3):328-341. doi: 10.1002/sctm.19-0173. Epub 2019 Nov 18.
2019
Martik ML, Gandhi S, Uy BR, Gillis JA, Green SA, Simoes-Costa M, Bronner ME. Evolution of the new head by gradual acquisition of neural crest regulatory circuits. Nature. 2019 Oct;574(7780):675-678. doi: 10.1038/s41586-019-1691-4. Epub 2019 Oct 23.
Hockman D, Chong-Morrison V, Green SA, Gavriouchkina D, Candido-Ferreira I, Ling ITC, Williams RM, Amemiya CT, Smith JJ, Bronner ME, Sauka-Spengler T. A genome-wide assessment of the ancestral neural crest gene regulatory network. Nat Commun. 2019 Oct 16;10(1):4689. doi: 10.1038/s41467-019-12687-4.
Prummel KD, Hess C, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Czarkwiani A, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C. A conserved regulatory program initiates lateral plate mesoderm emergence across chordates. Nat Commun. 2019 Aug 26;10(1):3857. doi: 10.1038/s41467-019-11561-7.
Tang W, Martik ML, Li Y, Bronner ME. Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish. Elife. 2019 Aug 8;8:e47929. doi: 10.7554/eLife.47929.
Moghadasi Boroujeni S, Koontz A, Tseropoulos G, Kerosuo L, Mehrotra P, Bajpai VK, Selvam SR, Lei P, Bronner ME, Andreadis ST. Neural crest stem cells from human epidermis of aged donors maintain their multipotency in vitro and in vivo. Sci Rep. 2019 Jul 5;9(1):9750. doi: 10.1038/s41598-019-46140-9.
Soldatov R, Kaucka M, Kastriti ME, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Häring M, Dyachuk V, Bock C, Farlik M, Piacentino ML, Boismoreau F, Hilscher MM, Yokota C, Qian X, Nilsson M, Bronner ME, Croci L, Hsiao WY, Guertin DA, Brunet JF, Consalez GG, Ernfors P, Fried K, Kharchenko PV, Adameyko I. Spatiotemporal structure of cell fate decisions in murine neural crest. Science. 2019 Jun 7;364(6444):eaas9536. doi: 10.1126/science.aas9536.
Parker HJ, Bronner ME, Krumlauf R. An atlas of anterior hox gene expression in the embryonic sea lamprey head: Hox-code evolution in vertebrates. Dev Biol. 2019 Sep 1;453(1):19-33. doi: 10.1016/j.ydbio.2019.05.001. Epub 2019 May 6.
Diaz RE Jr, Shylo NA, Roellig D, Bronner M, Trainor PA. Filling in the phylogenetic gaps: Induction, migration, and differentiation of neural crest cells in a squamate reptile, the veiled chameleon (Chamaeleo calyptratus). Dev Dyn. 2019 Aug;248(8):709-727. doi: 10.1002/dvdy.38. Epub 2019 Apr 29.
Sánchez-Vásquez E, Bronner ME, Strobl-Mazzulla PH. Epigenetic inactivation of miR-203 as a key step in neural crest epithelial-to-mesenchymal transition. Development. 2019 Apr 11;146(7):dev171017. doi: 10.1242/dev.171017.
Tang W, Li Y, Gandhi S, Bronner ME. Multiplex clonal analysis in the chick embryo using retrovirally-mediated combinatorial labeling. Dev Biol. 2019 Jun 1;450(1):1-8. doi: 10.1016/j.ydbio.2019.03.007. Epub 2019 Mar 15.
Parker HJ, De Kumar B, Green SA, Prummel KD, Hess C, Kaufman CK, Mosimann C, Wiedemann LM, Bronner ME, Krumlauf R. A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates. Nat Commun. 2019 Mar 13;10(1):1189. doi: 10.1038/s41467-019-09197-8.
Hutchins EJ, Bronner ME. Draxin alters laminin organization during basement membrane remodeling to control cranial neural crest EMT. Dev Biol. 2019 Feb 15;446(2):151-158. doi: 10.1016/j.ydbio.2018.12.021. Epub 2018 Dec 21.
2018
Gandhi S and Bronner ME. Insights into neural crest development from studies of avian embryos. 2018 Int J Dev Biol. 62(1-2-3):183-194. doi: 10.1387/ijdb.180038sg.
2017
Lignell A*, Kerosuo L*, Streichan SJ, Cai L, Bronner ME. Identification of a neural crest stem cell niche by Spatial Genomic Analysis. Nat Commun. 2017 28;8(1):1830. doi: 10.1038/s41467-017-01561-w.
Li, Y., Li. A., Junge, J., and Bronner, M.E. Planar cell polarity signaling coordinates oriented cell division and cell rearrangement in clonally expanding growth plate cartilage. 2017. eLife e23279.
Gandhi S, Piacentino ML, Vieceli FM, Bronner ME. Optimization of CRISPR/Cas9 genome editing for loss-of-function in the early chick embryo. 2017 Dev Biol. 432(1):86-97. doi: 10.1016/j.ydbio.2017.08.036.
Uribe, R., Hong, S.S., and Bronner M.E. Retinoic acid temporally orchestrates colonization of the gut by vagal neural crest cells. 2017. Dev. Biol. 433(1):17-32
Suarez-Bregua, P., Saxena, A., Bronner, M.E., Moran, P. and Rotllant, J. 2017. Targeted Pth4-expressing cell ablation impairs skeletal mineralization in zebrafish. PLoS One: e0186444.
Martik, M. and Bronner, ME. Regulatory Logic Underlying Diversification of the Neural Crest. 2017. Trends in Genetics (17)30132-4.
Green SA, Uy BR and Bronner ME. Ancient evolutionary origin of vertebrate enteric neurons from trunk-derived neural crest. Nature 2017 Mar 20. doi: 10.1038/nature21679
Roellig D, Tan-Cabugao J, Esaian S, Bronner ME. Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells. Elife. 2017 Mar 29;6. pii: e21620. doi: 10.7554/eLife.21620.
Chen J, Tambalo M, Barembaum M, Ranganathan R, Simões-Costa M, Bronner ME, Streit A. A systems level approach reveals new gene regulatory modules in the developing ear. 2017. Development 44(8):1531-1543
Bajpai VK, Kerosuo L, Tseropoulos G, Cummings KA, Wang X, Lei P, Liu B, Liu S, Popescu G, Bronner ME, Andreadis ST. Reprogramming Postnatal Human Epidermal Keratinocytes toward Functional Neural Crest Fates. 2017. Stem Cells35(5):1402-1415
Murko C and Bronner ME. Tissue specific regulation of the chick Sox10E1 enhancer by different Sox family members. 2017. Dev Biol. Feb 1;422(1):47-57. doi: 10.1016/j.ydbio.2016.12.004
Suarez-Bregua, P, Torres-Nunez, E, Saxena, A., Gueerreiro, P, Braasch, I, Prober, D., Moran, P., Cerda-Reverter, J., Du., S, Adrio, F., Power, D, Cannario, A., Postlethweit, J, Bronner, M., Canestro C. and Rotllant, J. Pth4, an ancient Parathyroid Hormone lost in eutherian mammals, reveals a new brain-to-bone signaling pathway. 2017. FASEB Journal 31(2):569-583.
2016
Kerosuo L and Bronner ME. cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool. 2016. Cell Reports. Dec 6;17(10):2648-2659. doi: 10.1016/j.celrep.2016.11.025
Simoes-Costa M and Bronner ME. Reprogramming of avian neural crest axial identity and cell fate. Science. 2016 Jun 24;352(6293):1570-3. doi: 10.1126/science.aaf2729.
Uribe RA, Gu T and Bronner ME. A novel subset of enteric neurons revealed by ptf1a:GFP in the developing zebrafish enteric nervous system. Genesis 2016 Feb 10. doi: 10.1002/dvg.22927
Roellig D and Bronner ME. The epigenetic modifier DNMT3A is necessary for proper otic placode formation. Developmental Biology 2016 Jan 28. pii: S0012-1606(16)30038-0. doi: 10.1016/j.ydbio.2016.01.034.
2015
Uribe RA*, Buzzi AL*, Strobl-Mazzulla and Bronner ME. Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression. Journal of Cell Biology. 2015 Nov 23;211(4):815-27. doi: 10.1083/jcb.201503071
Kerosuo L, Nie S, Bajpai R, Bronner ME. Crestospheres: Long-Term Maintenance of Multipotent, Premigratory Neural Crest Stem Cells. Stem Cell Reports. 2015 Sep 29 pii: S2213-6711(15)00251-9. doi: 10.1016/j.stemcr.2015.08.017.
Uribe RA and Bronner ME. Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development. Molecular Biology of the Cell. 2015 Sep 9. doi:10.1091/mbc.E15-02-0112.
Simoes-Costa M, Stone M and Bronner ME. Axud1 Integrates Wnt Signaling and Transcriptional Inputs to Drive Neural Crest Formation. Developmental Cell. 2015 Aug 5. pii: S1534-5807(15)00451-7. doi: 10.1016/j.devcel.2015.06.024.
Green, SA, Simoes-Costa M, and Bronner ME. Evolution of vertebrates as viewed from the crest. Nature. 2015 Apr 23, 2015.
Nie, S and Bronner ME. Dual developmental role of transcriptional regulator Ets1 in Xenopus cardiac vs. heart mesoderm. Cardiovas Res. 2015 Feb 17.
Hochgreb-Hägele T, Koo DE, Bronner ME. Znf385C mediates a novel p53-dependent transcriptional switch to control timing of facial bone formation. Dev Biol. 2015 Apr 1.
Simoes-Costa M and Bronner ME. Establishing a neural crest identify: a gene regulatory recipe. Development. 2015 Jan 15.
Uy BR, Simoes-Costa M, Koo DE, Sauka-Spengler T, Bronner ME. Evolutionarily conserved role for SoxC genes in neural crest specification and neuronal differentiation. Dev Biol. 2015 Jan 15.
2014
Hu N, Strobl-Mazzulla PH, Simoes-Costa M, Sánchez-Vásquez E, Bronner ME. DNA methyltransferase 3B regulates duration of neural crest production via repression of Sox10. PNAS. 2014 Dec 16.
Ezin M, Barembaum M, Bronner ME. Stage-dependent plasticity of the anterior neural folds to form neural crest. Differentiation. 2014 Sep-Oct.
Saxena A, Bronner ME. A novel HoxB cluster protein expressed in the hindbrain and pharyngeal arches. Genesis. 2014 Oct.
Wang K, Milkie DE, Saxena A, Engerer P, Misgeld T, Bronner ME, Mumm J, Betzig E. Rapid adaptive optical recovery of optimal resolution over large volumes. Nature Methods. 2014 Jun;11(6):625-8. doi: 10.1038/nmeth.2925.
Green SA and Bronner ME. The lamprey: a jawless vertebrate model system for examining origin of the neural crest and other vertebrate traits. Differentiation. 2014 Jan-Feb;87(1-2):44-51. doi: 10.1016/j.diff.2014.02.001
Hochgreb-Hägele T, Koo DE, Das NM, Bronner ME. Zebrafish stem/progenitor factor msi2b exhibits two phases of activity mediated by different splice variants. Stem Cells. 2014 Feb;32(2):558-71. doi: 10.1002/stem.1583
Simões-Costa M, Tan-Cabugao J, Antoshechkin I, Sauka-Spengler T, Bronner ME. Transcriptome analysis reveals novel players in the cranial neural crest gene regulatory network. Genome Res. 2014 Feb;24(2):281-90. doi: 10.1101/gr.161182.113
2013
Kerosuo L and Bronner ME. Biphasic influence of Miz1 on neural crest development by regulating cell survival and apical adhesion complex formation in the developing neural tube. Mol Biol Cell. 2013 Dec 4.
Rogers CD, Saxena A, Bronner ME. Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT. J Cell Biol. 2013 Dec 9;203(5):835-47. doi: 10.1083/jcb.201305050. Epub 2013 Dec 2.
Barembaum M, Bronner ME. Identification and dissection of a key enhancer mediating cranial neural crest specific expression of transcription factor, Ets-1. Dev Biol. 2013 Oct 15.
Saxena A, Peng BN, Bronner ME. Sox10-dependent neural crest origin of olfactory microvillous neurons in zebrafish. eLife, 2:e00336 (2013). dx.doi.org/10.7554/eLife.00336
Simões-Costa MS, McKeown SJ, Tan-Cabugao J, Sauka-Spengler T, Bronner ME. Dynamic and Differential Regulation of Stem Cell Factor FoxD3 in the Neural Crest Is Encrypted in the Genome. PLoS Genet. 2012 Dec;8(12):e1003142. doi: 10.1371/journal.pgen.1003142. Epub 2012 Dec 20.
Rogers CD, Phillips JL, Bronner ME (2012). Elk3 is essential for the progression from progenitor to definitive neural crest cell. Dev Biol. 2012 Dec 22. pii: S0012-1606(12)00675-6. doi: 10.1016/j.ydbio.2012.12.009. Feb 15, 2012.
Hochgreb-Hägele T, Bronner ME (2012). A novel FoxD3 gene trap line reveals neural crest precursor movement and a role for FoxD3 in their specification. Dev Biol. 2013 Feb 1;374(1):1-11. doi: 10.1016/j.ydbio.2012.11.035. Feb 1, 2012.
2012
Hu N, Strobl-Mazzulla P, Sauka-Spengler T, Bronner ME (2012). DNA methyltransferase3A as a molecular switch mediating the neural tube-to-neural crest fate transition. Genes Dev. 2012 Nov 1;26(21):2380-5. doi: 10.1101/gad.198747.112.
Jayasena CS, Bronner ME (2012). Rbms3 functions in craniofacial development by posttranscriptionally modulating TGF-β signaling. J Cell Biol. 2012 Oct 29;199(3):453-66. doi: 10.1083/jcb.201204138. Epub 2012 Oct 22.
Strobl-Mazzulla PH, Bronner ME (2012). A PHD12-Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition. J Cell Biol. 2012 Sep 17;198(6):999-1010. doi: 10.1083/jcb.201203098.
2011
Trinh le A, Hochgreb T, Graham M, Wu D, Ruf-Zamojski F, Jayasena CS, Saxena A, Hawk R, Gonzalez-Serricchio A, Dixson A, Chow E, Gonzales C, Leung HY, Solomon I, Bronner-Fraser M, Megason SG, Fraser SE. (2011) A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Genes Dev. Nov 1;25(21):2306-20. PMID: 22056673.
Betancur P, Sauka-Spengler T, Bronner M (2011) A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs. Development. 2011 Jul 20 PMID: 21775416
Haming D., Simoes-Costa M., Uy B., Sauka-Spengler T., Bronner ME. (2011) Expression of sympathetic nervous system genes in lamprey suggests their recruitment for specification of a new vertebrate feature. PLoS One. 2011;6(10):e26543. PMID:22046306
Jayasena CS, Trinh LA, Bronner M. (2011) Live imaging of endogenous Collapsin response mediator protein-1 expression at subcellular resolution during zebrafish nervous system development. Gene Expr Patterns. May 24 PMID: 21628002
McCabe, K.L. and Bronner-Fraser, M. (2011) Molecular and tissue interactions governing induction of cranial ectodermal placodes. Dev. Biol. 332:189-95 PMID: 19500565
Nie S., Kee Y., Bronner-Fraser M. (2011) Caldesmon regulates actin dynamics to influence cranial neural crest migration in Xenopus. Mol Biol Cell. 22, 3355-65. PMID: 21795398
Nikitina N., Tong L., Bronner ME. (2011) Ancestral network module regulating prdm1 expression in the lamprey neural plate border. Dev Dyn. 240, 2265-71. PMID: 21932309
